Understanding primary ovarian insufficiency:
When your ovaries slow down too soon
Is this menopause?
If your periods have become irregular or stopped altogether, and you’re under 40, you might be wondering: Is this menopause?
The answer is: not quite. It could be something called primary ovarian insufficiency (POI), sometimes referred to as premature ovarian failure. And while the name sounds confronting, understanding what’s happening can help you take back some control.
Understanding
What is primary ovarian insufficiency?
Primary ovarian insufficiency (POI) happens when the ovaries stop working properly before the age of 40. That means they may no longer release eggs regularly or produce the usual levels of hormones like oestrogen and progesterone.
POI is not the same as menopause. In menopause, ovarian function stops completely and permanently. With POI, it’s often unpredictable. Some people still ovulate occasionally. Others may not ovulate at all. You might have a period one month and none for the next few. That inconsistency is part of what makes POI so complex.
Primary ovarian insufficiency symptoms
What are the symptoms?
POI can look a lot like menopause but it may also come with its own set of emotional and fertility-related challenges.
Changes in your cycle:
- Irregular or skipped periods
- Lighter or shorter periods
- Periods stopping altogether
Hormonal symptoms:
- Hot flushes or night sweats
- Vaginal dryness or discomfort
- Mood swings or irritability
- Low libido
- Trouble sleeping
Fertility concerns:
- Difficulty falling pregnant
- No clear pattern of ovulation
If you’ve been trying to conceive and things aren’t happening as expected, POI might be one of the causes we will explore.
What causes POI?
In many cases, the cause is unknown. But some known contributors include:
Autoimmune conditions
(where the immune system attacks the ovaries)
Genetic conditions
(e.g. Fragile X syndrome, Turner syndrome)
Certain infections or environmental toxins
Chemotherapy or radiation therapy
Surgery involving the ovaries
For many, though, there’s no clear trigger and that uncertainty can be one of the hardest parts.
Why it’s both a gynaecology and fertility issue
POI sits at the crossroads of reproductive and hormonal health. You might first notice something’s off because of:
- Irregular periods
- Hot flushes
- Vaginal dryness
- Mood changes
- Fertility struggles
Your GP or gynaecologist may order blood tests such as:
- Follicle-stimulating hormone (FSH)
- Oestrogen levels
- Anti-Müllerian hormone (AMH)
- Thyroid function
- Prolactin
If you’re trying to conceive, your fertility specialist will explore whether any remaining ovarian activity could support pregnancy or whether options like IVF with donor eggs, assisted conception, or fertility preservation may be appropriate.
How is POI managed?
While there’s currently no way to reverse POI, there are several ways to support your physical, reproductive, and emotional wellbeing.
Hormone therapy:
- Hormone replacement therapy (HRT) or the combined pill may be recommended
- These treatments help replace missing oestrogen, protect bone density, support heart health, and ease symptoms like hot flushes or vaginal dryness
Fertility planning:
- Some people with POI still ovulate occasionally so spontaneous pregnancy, while less likely, is possible
- For others, options like donor egg IVF may be considered
- As a fertility specialist, I can help explore what’s right for you, based on your goals and hormone levels
Emotional and mental health support:
- A POI diagnosis can bring up grief, shock, and feelings of loss
- Counselling, peer support groups, and talking with others who’ve experienced the same thing can make a big difference
What people are saying
Here are some anonymous reflections from people living with POI:
- “My periods stopped in my mid 30s. At first, I thought it was stress. Then came the night sweats.”
- “It was such a shock to be told I might not be able to have children. I needed time to sit with that.”
- “I’m not in menopause but it feels a lot like it some days.”
These experiences are real and if they sound familiar, you’re not alone.
Early menopause Perth
What you can do next
Track your symptoms
Write down when your periods happen (or don’t), and note things like hot flushes, sleep changes, or low mood.
Ask the right questions
When you see your GP, you might ask: Could this be POI? What blood tests can help us find out?
Know your options
You don’t need to have all the answers right now. A gynaecologist or fertility specialist can help you understand what’s possible and what to do next.
Menopause specialist Perth
Let’s talk about your options
Being told your ovaries aren’t working as expected can feel confronting—especially when it comes out of the blue. But there are ways to manage your health, understand your fertility options, and feel more in control.
You don’t have to figure this out alone. Here’s what you can do today:
- Follow me on Instagram for educational content and women’s health conversations.
- Book a consultation if you’d like to talk things through
- Download a symptom tracker to bring along to your GP or specialist appointment. As a founder of Charli.health, I’ve worked on a symptom tracker designed to help you log your cycle and symptoms. It’s a simple tool you can use to support conversations with your healthcare team.